Long noncoding RNAs (lncRNAs), which is essential in regulating multiple biological functions, have been found to have pivotal roles in immune regulation. Since immune reaction and immunocytes are the key part in periodontitis progression, we aim to investigate the underlying lncRNA-immunity regulatory network of periodontitis.A series of bioinformatic algorithms were used to identify immune-related lncRNAs in periodontitis. Infiltrating immunocyte were calculated by MCP-count. Pathway activity were estimated by the GSVA. The relationships between immune-related lncRNA and periodontitis features were investigated including immune gene categories, perturbated lncRNAs, immunocytes and pathways. Immune-related periodontitis subtypes were identified by ConsensusClusterPlus algorithm. Immunocytes related gene-lncRNA modules were identified by WGCNA.An integrated algorithm and pipeline to identify immune-related lncRNAs was developed and 1059 immune-related lncRNAs in 14 immune categories were identified, 291 of them were perturbated in periodontitis. An independent validation set verified the robustness of immune-related lncRNAs. A higher proportion of immune-related lncRNAs are correlated with immunocyte infiltration.
KT 5823 |
B6673-.1 |
ApexBio |
100 µg |
EUR 190 |
KT 5823 |
B6673-.25 |
ApexBio |
250 µg |
EUR 361 |
KT 5720 |
B9002-.05 |
ApexBio |
50 µg |
EUR 145 |
KT 5720 |
B9002-.1 |
ApexBio |
100 µg |
EUR 232 |
KT 5720 |
B9002-.25 |
ApexBio |
250 µg |
EUR 483 |
KT 5720 |
B9002-.5 |
ApexBio |
500 µg |
EUR 818 |
mmu-miR-6945-3p Primers |
MPM01702 |
ABM |
150 ul / 10 uM |
EUR 121 |
mmu-miR-6945-5p Primers |
MPM01703 |
ABM |
150 ul / 10 uM |
EUR 121 |
mmu-miR-6945-3p miRNA Antagomir |
MNM02638 |
ABM |
2 x 5.0 nmol |
EUR 329 |
mmu-miR-6945-5p miRNA Antagomir |
MNM02639 |
ABM |
2 x 5.0 nmol |
EUR 329 |
mmu-miR-6945-3p miRNA Inhibitor |
MIM02638 |
ABM |
2 x 5.0 nmol |
EUR 176 |
mmu-miR-6945-5p miRNA Inhibitor |
MIM02639 |
ABM |
2 x 5.0 nmol |
EUR 176 |
Plasminogen Receptor (KT) (PLGRKT) Antibody |
20-abx318476 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
KT 5823 (PKG kinase inhibitor) |
SIH-458-100UG |
Stressmarq |
100 µg |
EUR 205 |
- KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
- Show more
|
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml). |
KT 5823 (PKG kinase inhibitor) |
SIH-458-500UG |
Stressmarq |
500 µg |
EUR 569 |
- KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
- Show more
|
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml). |
S- Adenosylhomocysteine Antibody (Clone # 301-10) |
6945-25 |
Biovision |
|
EUR 218 |
LRRC37A3 Blocking Peptide |
33R-6945 |
Fitzgerald |
100 ug |
EUR 180 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of LRRC37A3 antibody, catalog no. 70R-7010 |
FMR1 antibody |
10R-6945 |
Fitzgerald |
100 ul |
EUR 726 |
Description: Mouse monoclonal FMR1 antibody |
PPAPDC2 antibody |
70R-6945 |
Fitzgerald |
50 ug |
EUR 467 |
Description: Rabbit polyclonal PPAPDC2 antibody raised against the N terminal of PPAPDC2 |
Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt |
GA-E0451RT-48T |
GenAsia Biotech |
48T |
EUR 317 |
Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt |
GA-E0451RT-96T |
GenAsia Biotech |
96T |
EUR 496 |
Factor XI Antibody Pair |
55R-FAC11-KT |
Fitzgerald |
5 plates |
EUR 745 |
Description: Factor XI antigen Matched Pair antibody Set for ELISA |
Factor IX Antibody Pair |
55R-FAC9-KT |
Fitzgerald |
5 plates |
EUR 760 |
Description: Factor IX antigen Matched Pair antibody Set for ELISA |
Fibrinogen Matched Pair antibody Set |
55R-FIBRINO-KT |
Fitzgerald |
set |
EUR 833 |
Description: Fibrinogen Matched Pair antibody Set for detection of Human Fibrinogen in the research laboratory |
Mouse RANKL ELISA Kit |
55R-MRANKL-KT |
Fitzgerald |
1 kit |
EUR 658 |
Description: ELISA kit for detection of Mouse RANKL in the research laboratory |
VWF Antibody Pair |
55R-VWF-KT |
Fitzgerald |
5 plates |
EUR 775 |
Description: VWF antigen Matched Pair antibody Set for ELISA |