Protein promiscuity in drug discovery, drug-repurposing and antibiotic resistance.

Proteins are supposed to bind to their substrates/ligands in a specific manner via their pre-formed binding sites, according to classical biochemistry. In recent years, several types of deviations from this norm have been observed and called promiscuous behavior. Enzymatic promiscuities allow several biochemical functions to be carried out by the same enzyme. The promiscuous activity can also be the origin of “new proteins” via gene duplication. In more recent years, proteins from prokaryotes, eukaryotes and viruses have been found to have intrinsic disorder and lack a preformed binding site. Intrinsic disorder is exploited in regulatory proteins such as those that are involved in transcription and signal transduction.

KT 5823
B6673-.1	ApexBio	100 µg	EUR 190

KT 5823
B6673-.25	ApexBio	250 µg	EUR 361

KT 5720
B9002-.05	ApexBio	50 µg	EUR 145

KT 5720
B9002-.1	ApexBio	100 µg	EUR 232

KT 5720
B9002-.25	ApexBio	250 µg	EUR 483

KT 5720
B9002-.5	ApexBio	500 µg	EUR 818

PST- KT
PVT11358	Lifescience Market	2 ug	EUR 370

gp100 (619–627)
5-01246	CHI Scientific	4 x 5mg	Ask for price

Gab1 (Ab-627) Antibody
21283-100ul	SAB	100ul	EUR 252

Gab1 (Ab-627) Antibody
21283-50ul	SAB	50ul	EUR 187

GAB1 (Ab-627) Antibody
CSB-PA582871-	Cusabio		EUR 335
Form: liquid Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibo Show more
Description: A polyclonal antibody against GAB1 (Ab-627). Recognizes GAB1 (Ab-627) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

GAB1 (Ab-627) Antibody
CSB-PA582871-100ul	Cusabio	100ul	EUR 316
Form: liquid Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibo Show more
Description: A polyclonal antibody against GAB1 (Ab-627). Recognizes GAB1 (Ab-627) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

gp100 (619-627) Peptide
20-abx266111	Abbexa	EUR 411.00 EUR 662.00 EUR 314.00	10 mg 25 mg 5 mg
Shipped within 5-10 working days.

anti-Gab1 (Ab-627)
LF-PA20172	Abfrontier	100 ul	EUR 334
Description: Rabbit polyclonal to Gab1

hsa-miR-627 Primers
MPH01927	ABM	150 ul / 10 uM	EUR 121

Plasminogen Receptor (KT) (PLGRKT) Antibody
20-abx318476	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

KT 5823 (PKG kinase inhibitor)
SIH-458-100UG	Stressmarq	100 µg	EUR 205
KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen Show more
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

KT 5823 (PKG kinase inhibitor)
SIH-458-500UG	Stressmarq	500 µg	EUR 569
KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen Show more
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

Gab1 (Ab-627) Conjugated Antibody
C21283	SAB	100ul	EUR 397

hsa-miR-627 miRNA Inhibitor
MIH03272	ABM	2 x 5.0 nmol	EUR 176

hsa-miR-627 miRNA Antagomir
MNH03272	ABM	2 x 5.0 nmol	EUR 329

hsa-miR-627-3p Primers
MPH03390	ABM	150 ul / 10 uM	EUR 121

hsa-miR-627-5p Primers
MPH03391	ABM	150 ul / 10 uM	EUR 121

Recombinant (E.Coli) purified Mycobacterium Tuberculosis Heat Shock Protein 65 (hsp65/groEL-2/Cpn60-2)
RP-627	Alpha Diagnostics	10 ug	EUR 286

Zinc Finger Protein 627 (ZNF627) Antibody
abx037044-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

Zinc Finger Protein 627 (ZNF627) Antibody
20-abx306221	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

hsa-miR-627-3p miRNA Inhibitor
MIH03273	ABM	2 x 5.0 nmol	EUR 176

hsa-miR-627-5p miRNA Inhibitor
MIH03274	ABM	2 x 5.0 nmol	EUR 176

hsa-miR-627-3p miRNA Antagomir
MNH03273	ABM	2 x 5.0 nmol	EUR 329

hsa-miR-627-5p miRNA Antagomir
MNH03274	ABM	2 x 5.0 nmol	EUR 329

Anti-STAT4 (aa 613-627) antibody
STJ72162	St John's Laboratory	100 µg	EUR 359

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
GA-E0451RT-48T	GenAsia Biotech	48T	EUR 317

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
GA-E0451RT-96T	GenAsia Biotech	96T	EUR 496

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
QY-E11201	Qayee Biotechnology	96T	EUR 361

Mouse Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
QY-E20317	Qayee Biotechnology	96T	EUR 361

Zinc Finger Protein 627 (ZNF627) Antibody (HRP)
20-abx306222	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Zinc Finger Protein 627 (ZNF627) Antibody (FITC)
20-abx306223	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Zinc Finger Protein 627 (ZNF627) Antibody (Biotin)
20-abx306224	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Polyclonal STAT4 (aa 613-627) Antibody (internal region)
APG00648G	Leading Biology	0.1mg	EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human STAT4 (aa 613-627) (internal region). This antibody is tested and proven to work in the following applications:

Human Zinc finger protein 627, ZNF627 ELISA KIT
ELI-14719h	Lifescience Market	96 Tests	EUR 824

Recombinant Caenorhabditis Elegans B0280.2 Protein (aa 1-627)
VAng-Ly3032-inquire	Creative Biolabs	inquire	Ask for price
Description: Caenorhabditis Elegans uncharacterized protein B0280.2 (B0280.2), partial, recombination protein.

Recombinant Caenorhabditis Elegans B0361.3 Protein (aa 1-627)
VAng-Ly3051-inquire	Creative Biolabs	inquire	Ask for price
Description: Caenorhabditis Elegans uncharacterized protein B0361.3 (B0361.3), partial, recombination protein.

Recombinant Mycobacterium Smegmatis MSMEG_5130 Protein (aa 28-627)
VAng-Yyj4733-inquire	Creative Biolabs	inquire	Ask for price
Description: Mycobacterium Smegmatis (strain ATCC 700084 / mc(2)155) Probable monoacyl phosphatidylinositol tetramannoside-binding protein LpqW (MSMEG_5130), recombinant protein.

Recombinant Pseudomonas Aeruginosa thiC Protein (aa 1-627)
VAng-Cr0715-inquire	Creative Biolabs	inquire	Ask for price
Description: Pseudomonas Aeruginosa (strain PA7) phosphomethylpyrimidine synthase (thiC), recombinant protein.

Recombinant Shigella Flexneri mutL Protein (aa 1-627)
VAng-Lsx07960-inquire	Creative Biolabs	inquire	Ask for price
Description: Shigella Flexneri serotype 5b DNA mismatch repair protein mutL, recombinant protein.

Recombinant Clostridium Phytofermentans mnmG Protein (aa 1-627)
VAng-Lsx01361-inquire	Creative Biolabs	inquire	Ask for price
Description: Clostridium Phytofermentans tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, recombinant protein.

Human LRRC32 Protein (His 20-Asn 627) [Fc]
VAng-1903Lsx-100g	Creative Biolabs	100 µg	EUR 1178
Description: Human LRRC32 protein, human IgG1 Fc tag, expressed in human 293 cells. (Uniprot ID: Q14392-1)

Human LRRC32 Protein (His 20-Asn 627) [Fc]
VAng-1903Lsx-1mg	Creative Biolabs	1 mg	EUR 6924
Description: Human LRRC32 protein, human IgG1 Fc tag, expressed in human 293 cells. (Uniprot ID: Q14392-1)

Recombinant Treponema Pallidum TP_0179 Protein (aa 1-627)
VAng-Cr1348-inquire	Creative Biolabs	inquire	Ask for price
Description: Treponema Pallidum (strain Nichols) uncharacterized protein TP_0179 (TP_0179), recombinant protein.

Human pre-microRNA Expression Construct Lenti-miR-627
PMIRH627PA-1	SBI	Bacterial Streak	EUR 684
Category: MicroRNA Tools

Anti-Ms CD80 Purified
11-627-C100	ExBio	0.1 mg	EUR 113

Anti-ERBB2 (trastuzumab)-Aminocaproyl-MMAE ADC
ADC-W-627	Creative Biolabs	1mg	Ask for price
Description: This ADC product is comprised of an engineerd anti-ERBB2 antibody (trastuzumab with LLQGG tag at Fc) conjugated via a Aminocaproyl linker to MMAE

Factor XI Antibody Pair
55R-FAC11-KT	Fitzgerald	5 plates	EUR 745
Description: Factor XI antigen Matched Pair antibody Set for ELISA

Factor IX Antibody Pair
55R-FAC9-KT	Fitzgerald	5 plates	EUR 760
Description: Factor IX antigen Matched Pair antibody Set for ELISA

Fibrinogen Matched Pair antibody Set
55R-FIBRINO-KT	Fitzgerald	set	EUR 833
Description: Fibrinogen Matched Pair antibody Set for detection of Human Fibrinogen in the research laboratory

Mouse RANKL ELISA Kit
55R-MRANKL-KT	Fitzgerald	1 kit	EUR 658
Description: ELISA kit for detection of Mouse RANKL in the research laboratory

VWF Antibody Pair
55R-VWF-KT	Fitzgerald	5 plates	EUR 775
Description: VWF antigen Matched Pair antibody Set for ELISA

gp100 (619-627) (AA: Arg-Leu-Met-Lys-Gln-Asp-Phe-Ser-Val) (MW: 1123.35)
SP-88276-5	Alpha Diagnostics	5 mg	EUR 225